Dengue fever is a global concern - we urge the United Nations to designate a World Dengue Day at its General Assembly in September 2019
Treatment with antibiotics depletes the gut microbiota in mice, making them more susceptible to infection by dengue, zika and west nile virus.
Dengue is the most common arthropod-borne infection worldwide, affecting at least 50 million people every year and endemic in more than 100 countries. The dengue virus is a single-stranded RNA virus with four major serotypes. Infection with one serotype confers homotypic immunity but not heterologous immunity, and secondary infection with another serotype may lead to more severe disease.
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